Page 61 - ITU Journal Future and evolving technologies Volume 2 (2021), Issue 3 – Internet of Bio-Nano Things for health applications
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ITU Journal on Future and Evolving Technologies, Volume 2 (2021), Issue 3




                                   Table 2 – Summary of transmission and detection in static MC without drift
            Reference  Modulation      Detection                     Symbol‑         Coherent/    Complexity
                                                                     by‑symbol       Non‑coherent
                                                                     (Sbs)/Sequence  detection
                                                                     (Seq) detector
            [33]       MoSK            i) MAP detection without ISI  Sbs for i) and  Coherent     i) High
                                       ii) Viterbi detection with ISI  Seq for ii)                ii) Very high
            [35]       Binary PAM      Log LRT for energy detection scheme Sbs       Coherent     High
            [37]       OOK             NP test (for separating very close bi‑ Sbs    Coherent     Low
                                       nary signals) and MF detector
            [39]       OOK             Amplitude and energy detection with Sbs       Non‑coherent  Low
                                        ixed threshold
            [34]       MoSK            MAP detection with noise whitening Sbs        Coherent     High
                                        ilter
            [40]       Rectangular pulse Adaptive receiver based on steepest Seq for i), ii) and Coherent  i) Very high
                       based OOK       descent algorithm for i) MAP detec‑ Sbs for iii), iv)      ii) High
                                       tion ii) Maximum likelihood detection                      iii) Low
                                       iii) MMSE equalizer iv) DFE                                iv) Moderate
            [41]       Binaryand quater‑ Log LRT for binary and M‑ary detec‑ Sbs     Coherent     High
                       nary ASK        tion
            [43]       Modulation based MAP rule using CTMP          Sbs             Coherent     Moderate
                       on chemical reac‑
                       tion rate
            [45]       MTSK            DFF                           Sbs             Coherent     High
            [86]       OOK             Cooperative detection with GLRT at Sbs        Coherent     High
                                       1st tier and OR fusion rule at 2nd tier
            [52]       Rectangular     Nonlinear adaptive threshold detec‑ Sbs       Non‑coherent  Low
                       pulsed based OOK  tion based on local geometry and en‑
                                       ergy difference of received signal
            [60]       Rectangular     Two layered detection for reduc‑ Seq          Non‑coherent  High
                       pulsed based OOK  ing the number of sequences to be
                                       searched
            [27]       OOK             ANN with Gradient‑Descent opti‑ Seq           Non‑coherent  High
                                       mization for weights
            [61]       OOK             Derivative based detection    Sbs             Non‑coherent  Moderate
            [63]       OOK and OSK     Suboptimal maximum likelihood de‑ Sbs         Non‑coherent  Moderate
                                       tector and ISI neglecting detector
            [96]       OOK             ANN with fuzzy threshold detection Sbs        Non‑coherent  High
                                       and polynomial approximation
            [29]       OOK             ANN detection with LM optimizer  Sbs          Non‑coherent  Moderate
            [71]       Rectangular pulse Binary  detection  with  iterative Sbs      Non‑coherent  Moderate
                       based OOK       method of ISI mitigation



          average detection i.e., an average of the output was calcu‑   Synchronous and asynchronous sensing techniques were
          lated then fed to the MAP detector for reducing the com‑   proposed  in  [114].  In  this  work,  two  different  nano‑
          plexity of the receiver.  In the third technique,  irst‑order   networks (each consisting of a single transmitter and re‑
          arrival time was used as the test statistic.         ceiver pair) were assumed inside a blood vessel.  At the
                                                               receiver, energy detection was employed for detecting the
          In [104], the transmitter emitted molecules using the OOK   molecules. Besides, sensing based on long and short sens‑
          modulation scheme. In this work, the channel was similar   ing windows in the case of synchronous sensing was also
          to  the  vein  and  at  the  receiver,  maximum  likelihood  se‑   proposed.  Moreover, the Bayesian approach was used to
                                                               derive the likelihood ratio test in the case when the two
          quence  detection  was  used.  The  BER  performance  was
                                                               networks were not synchronized. In [115], sampling time
          evaluated  in  the  presence  of  a  periodic  force  generated
                                                               i.e., the number of samples taken at the receiver was opti‑
          due to heart pumping, where periodic force was modeled
                                                               mized to minimize the error probability with OOK modu‑
          as  a  sinusoidal  wave.  Also,  the  performance  evaluation
                                                               lated transmission. For decoding, an energy detector was
          was done considering different sinusoidal phases and the
                                                               used at the receiver.
          different  size  of  transmitted  molecules.  Simulation  re‑
          sults  demonstrated  that  performance  improvement  can
          be achieved by the appropriate selection of release time
          of molecules and their size.

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