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2024 ITU Kaleidoscope Academic Conference




           explored  to  enable  intelligent  and  personalized  health   Providing personalized health services requires the ability to
           interventions  across  various  domains,  including  disease   retrieve  relevant  and  trustworthy  information  based on  an
           diagnosis, treatment planning, health monitoring, and patient   individual's  specific  context  and  needs.  Traditional
           engagement [8]. Machine learning models trained on large   knowledge retrieval approaches based on keyword matching
           medical datasets have shown promise in assisting clinicians   or  document  similarity  often  fail  to  capture  the  nuanced
           with diagnostic tasks, such as detecting cancers from medical   semantics and reasoning required for health-related queries.
           images [9], predicting adverse drug events from electronic   Semantic search techniques that leverage knowledge graphs,
           health records [10] and identifying mental health conditions   ontologies  and  embeddings  have  shown  promise  in
           from  EEG  data  [11].  Chatbots  and  conversational  agents   improving the relevance and coverage of health information
           powered by natural language processing are being developed   retrieval  [23],  [24].    These  approaches  can  enable  more
           to  provide  patient  education,  symptom  assessment,  and   precise  and  comprehensive  search  results  by  mapping
           treatment  recommendations  [12].  Computer  vision   queries  and  documents  to  structured  representations  that
           techniques  enable  new  assistive  technologies  for  visually   capture  entities,  relationships,  and  concepts.  Retrieval-
           impaired individuals [13] while AI-enabled robots support   augmented  generation  (RAG)  is  an  emerging  paradigm
           elder care and physical therapy [14]. However, current AI   combining knowledge retrieval and generative AI to enable
           applications in digital health largely rely on narrow, task-  more  informed  and  reliable  language  understanding  and
           specific models that are trained on limited, curated datasets.   generation [25]. RAG models use a retriever component to
           They  often  lack  the  breadth  of  knowledge,  contextual   find  relevant  context  from  an  external  knowledge  source,
           understanding, and reasoning capabilities needed to provide   which is then passed to a generator component to produce a
           truly  personalized  and  engaging  user  experiences.   contextually appropriate response.
           Generative  AI  models  that  can  leverage  vast  amounts  of
           general-purpose data offer a promising approach to bridge   Recent  work  has  demonstrated  the  potential  of  RAG  for
           this gap.                                          improving the factual accuracy and consistency of generative
                                                              models  in  open-domain  question  answering  [26]  and
           2.2   Generative AI and Large Language Models      dialogue  [27].  Applying  RAG  to  personalized  health
                                                              retrieval  can  enable  generative  models  to  access  curated,
           Generative AI refers to a class of AI models that can generate   domain-specific  knowledge  sources,  such  as  medical
           new  content,  such  as  text,  images,  or  audio,  by  learning   ontologies,  clinical  guidelines,  and  patient  education
           patterns  and  representations  from  large  datasets.  Recent   resources. By grounding generated content in verified health
           advances  in  deep  learning,  particularly  transformer   information, RAG can help ensure the reliability and safety
           architectures  [15],  have  enabled  the  development  of   of AI-driven health services. However, designing effective
           powerful  generative  language  models  that  can  understand   retrieval  mechanisms  that  can  handle  the  complexity  and
           and generate human-like text with remarkable coherence and   diversity  of  health queries,  while  preserving  user  privacy,
           fluency. Models like GPT-3 [4], BERT [16] and T5 [17] have   remains an open challenge.
           been  pre-trained  on  massive  text  corpora  from  the  web,
           books,  and  other  sources,  allowing  them  to  capture  rich   3.  RESEARCH METHODOLOGY
           knowledge about language, concepts, and reasoning patterns.
           By  fine-tuning  these  models  on  domain-specific  data  or   3.1   System Overview
           providing  them  with  contextual  prompts,  developers  can
           create intelligent applications that can engage in open-ended
           conversations, answer questions, summarize documents, and
           even write creative fiction. The potential of generative AI for
           enabling personalized digital services has been demonstrated
           in various domains, such as education [18], customer support
           [19] and mental health [20].

           Applying  generative  AI  in  high-stakes  domains  like
           healthcare also raises important challenges around reliability,
           safety, and ethical alignment.  LLMs can sometimes generate
           inaccurate, biased, or even harmful content, emphasizing the
           need  for  careful  prompt  engineering,  output  filtering,  and
           human  oversight  [21].  Another  critical  consideration  is
           ensuring privacy and security of sensitive health data used to
           train and deploy these models. Research on controllable and
           safe generation techniques, model interpretability, and value
           alignment is ongoing in the AI community [22].

           2.3   Knowledge Retrieval for Personalized Health         Figure 1 – System architecture diagram








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