Recommendation ITU-T Y.4484 specifies the framework to support web of objects (WoO) ontology based semantic data interoperability of e-health services in accordance with Recommendations ITU‑T Y.4452 and ITU-T Y.4563. Semantic data interoperability enables the various e-health systems to combine received information with other information resources and to process it in a manner that preserves meaning. In order to support the semantic data interoperability functions among e-health systems, this Recommendation applies the WoO framework in Recommendation ITU-T Y.4452 and the semantic data interoperability function in Recommendation ITU-T Y.4563.